Aquilos 2 Cryo FIB/SEM
Aquilos 2 Cryo FIB/SEM
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Cryo-electron tomography @ Cleveland
The Zhu Lab participated in the installation and validation of the Aquilos 2 cryo-FIB/SEM in CWRU. The lab has been using the Aquilos 1 since 2018 and produced its first high-quality in situ LLPS cryo-ET study in 2019 using the Aquilos 1, published in Nature in 2021 (PMID: 34040255)
Integrated Cryo-CLEM
Integrated Cryo-CLEM
In situ cryo-correlative light and electron microscopy (cryo-CLEM) for precise ROI identification before and after cryo-FIB milling. This system in CWRU was the third of its kind installed and validated in the United States by the Zhu Lab.
Titan Krois cryo-TEM
Titan Krois cryo-TEM
A state-of-the-art 300 kV cryogenic TEM for high-resolution structural visualization using cryo-ET. Cryo-ET data-collection scripts have been installed, optimized, and validated by the Zhu Lab.
We're NOW hiring, and JOIN US!
2 postdoctoral positions are immediately available!!!
Postdoctoral Candidates
We are looking for highly-motivated postdoctoral fellows to study the host-pathogen interaction in the cellular context by using cutting-edge cryo-ET with allied techniques, including cryo-FIB/SEM and cryo-CLEM.
Interested applicants should have a Ph.D. or equivalent degree in one of the following fields: structural biology, biochemistry, biophysics, microbiology, and cell biology. Prior experience in structural biology research is not required. To inquire, please email Dr. Zhu ( shiwei.zhu@case.edu ) with a cover letter describing your research interest, a recent CV, and the contact information of 2 academic referees.
Graduate Students
For graduate students interested in joining the lab, please look at our Biomedical Sciences Training Program at CWRU School of Medicine. Please submit application material that indicates that your priority program interest is the Department of Physiology and Biophysics, and Shiwei Zhu is the potential thesis advisor.
Visiting Scholars/Students
Please briefly describe your academic background and research interests to Dr. Zhu ( shiwei.zhu@case.edu ).
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